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NUCLEAR MEDICINE IN MOLECULAR IMAGING
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NUCLEAR MEDICINE IN MOLECULAR IMAGING
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Academic year 2024/2025
- Course ID
- BIO0251
- Teachers
- Enzo Terreno (Lecturer)
Gianluca Destro (Lecturer) - Year
- 2nd year
- Teaching period
- Second semester
- Type
- Related or integrative
- Credits/Recognition
- 6
- Course disciplinary sector (SSD)
- CHIM/03 - general and inorganic chemistry
- Delivery
- Formal authority
- Language
- English
- Attendance
- Obligatory
- Type of examination
- Oral
- Type of learning unit
- corso
- Prerequisites
- The course includes basic knowledge in the fields of organic synthesis, coordination chemistry, and nuclear chemistry.
- Propedeutic for
- The course is not a prerequisite for other courses
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Sommario del corso
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Course objectives
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Results of learning outcomes
Knowledge and Understanding: At the end of the course, students will be able to:
- Understand the main properties of radionuclides of interest in Nuclear Medicine;
- Know the main radiosynthesis and radiolabeling procedures for a given radionuclide;
- Understand the basic principles and characteristics of imaging technologies that use radiotracers;
- Know the main clinical applications of radiotracers in Nuclear Medicine, both diagnostic and theranostic.
Ability to Apply Knowledge and Understanding: At the end of the course, students will be able to:
- Choose the best radionuclide and radiotracer for specific diagnostic/theranostic clinical applications;
- Design the best radiosynthesis procedure based on the radionuclide of interest;
- Select the most useful imaging technique and methodology based on the clinical application of interest;
- Critically analyze PET/SPECT images to extract diagnostic information.
Autonomy of Judgment: At the end of the course, students will be able to:
- Set up and design a Nuclear Medicine imaging study for a specific clinical application (choice of radionuclide and imaging technique, radiolabeling, experimental planning).
Learning Ability:
- The acquisition of knowledge/skills gained in the course will be assessed during the examination.
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Program
Radiochemistry
History of Nuclear Medicine
Nuclear Chemistry
Radionuclide production
Chemistry of nitrogen and oxygen
Chemistry of carbon and hydrogen
Radiochemistry of fluorine-18
Radiochemistry of carbon-11 and iodine radionuclides
Chemistry of radiometals
Applications in Nuclear Medicine
Basic principles of imaging technologies using ionizing radiations (CT, PET, SPECT)
Signal quantification in PET/SPECT
Use of 18F-FDG in PET imaging
Applications of Nuclear Medicine in Neurology
Applications of Nuclear Medicine in Cardiology
Applications of Nuclear Medicine in Oncology beyond 18F-FDG
Radiotheranostics
Immuno-based radiotracers
Imaging inflammation/infections by PET/SPECT
Radio-guided surgery
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Course delivery
The course includes 48 hours of instruction delivered through in-class lectures. No exercises are plenned.
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Learning assessment methods
Learning assessment will be conducted through an oral exam. The evaluation is done on a scale of thirty. The exam is considered passed if a score of 18/30 is achieved.
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Support activities
All the material presented during the lessons, and supported by bibliographic material, will be uploaded to the teaching Moodle page and made available to students.Suggested readings and bibliography
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Teaching Modules
- RADIOCHEMISTRY (BIO0234A)
- RADIOTHERANOSTICS (BIO0234B)
- Enroll
- Open
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