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MEDICINAL CHEMISTRY B

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MEDICINAL CHEMISTRY B

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Academic year 2023/2024

Course ID
BIO0232B
Teachers
Sonja Visentin (Lecturer)
Giuseppe Ermondi (Lecturer)
Year
2nd year
Teaching period
Annual
Type
Related or integrative
Credits/Recognition
3
Course disciplinary sector (SSD)
CHIM/08 - pharmaceutical chemistry
Delivery
Formal authority
Language
English
Attendance
Optional
Type of examination
Oral
Type of learning unit
modulo
Modular course
MEDICINAL CHEMISTRY (BIO0232)
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Sommario del corso

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Course objectives

This module aims to provide students with the basic concepts of Medicinal Chemistry related to pharmacodynamics and ADME-Tox properties of drugs, preparatory to the acquisition of advanced skills in these fields covered in Module A of the course.

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Results of learning outcomes

KNOWLEDGE AND UNDERSTANDING

  •  Acquisition of theoretical an applicative skill concerning Medicinal Chemistry principles

APPLYING KNOWLEDGE AND UNDERSTANDING

  • Development of the ability to incorporate information from the study of 3D structures of molecules and from information obtained from servers specialised in the prediction of ADME-Tox properties into daily research work

MAKING JUDGEMENTS

  • Critical evaluation of the information obtained from 3D and web server analysis

COMMUNICATION SKILLS

  • Acquisition of oral and written communication of results as well as the ability to use graphical language

LEARNING SKILLS

  • Acquisition of autonomous learning capacity and self-assessment of its preparation
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Program

TOPICS COVERED IN THE COURSE

  • Introduction to the drugs targets and interaction drug-protein
  • Basic ADME-Tox concepts
  • Preparation of reliable 3D structures of drugs
  • In-silico analysis of drug-protein interaction
  • ADME-Tox properties predictors
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Course delivery

24-hours course, splitted in theoritical lessons and practical work

The attendance is optional but strongly recommended

The didactic material will be published on the Moodle platform

Communication with students takes place through e-mail and requires registration on the Moodle platform

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Learning assessment methods

A single oral examination for both modules


The oral exam focuses mainly on the theoretical aspects as well as the practical work done during the course in order to evaluate both the understanding of the basic principles and the student's ability to apply these principles to real contexts

 

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Support activities

At the beginning of each lesson, the lecturer is available to the students to discuss, repeat explanations and clarify what has already been explained during the previous lessons

The sharing of any doubts is strongly recommended to promote the common growing of all learners

Suggested readings and bibliography

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Slides will be provided to the students and articles will be suggested for further study of the course topics



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